Though OneDrive is a great tool - there can occasionally be issues which cause synchronization (between one of your devices and OneDrive) to fail.  This could impact a small number of files or folders, or it could stop the sync complete. 
Below are the various OneDrive status icons which indicate there may be an issue.  These will show in the taskbar or notification area (bottom right in Windows, top right in MacOS).  If you can't see any OneDrive icons in the taskbar or notification area, it could be that the icons have moved, or OneDrive isn't running. Learn more.
OneDrive Status Icons
Below are some of the more common OneDrive status icons, what they mean, and a link to details on how to resolve the issue.  For more information, see Microsoft's OneDrive Status Icon page.
Windows 
 OneDrive work/school sync error
  OneDrive work/school sync error
 
macOS
 OneDrive for Mac sync errors
  OneDrive for Mac sync errors
 
Windows File Explorer / macOS Finder
 OneDrive sync error
  OneDrive sync error
 OneDrive processing changes
  OneDrive processing changes
 File locked
  File locked 
Common 
 or
  or   OneDrive processing changes
  OneDrive processing changes
 or
  or   OneDrive paused
  OneDrive paused
 OneDrive not signed in
  OneDrive not signed in
 
OneDrive reset
If other issues have not worked, you can reset OneDrive.  This will not delete or alter, any data on your computer, or on OneDrive but resets the synchronization.  It's a catch-all troubleshooting step for most issues.
Last Resort / All Else Fails - Reset OneDrive Client